Which is a contraindication for the administration of tissue plasminogen activator (t-pa)?9/24/2023 ![]() ![]() The incidence of this condition is approximately 1.5 cases per 10,000 persons per year. Acute limb ischemia (ALI) may be the first manifestation of arterial disease in a previously asymptomatic patient or may occur as an acute event that causes symptomatic deterioration in a patient with antecedent lower extremity periphery artery disease (PAD) and intermittent claudication. Sudden loss or marked decrease in limb perfusion that threatens limb viability is a vascular emergency.
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